منابع مشابه
Epiphyseal Necrosis in Pituitary Gigantism
Drigalski and Diethelm (1937) recently described a case of gigantism, which showed degenerative changes in both hip joints. We have had an opportunity of observing a boy with similar symptoms, who is reported both on account of the rarity of these manifestations and in order to discuss the relation of the curious osseous changes to some bone diseases belonging to the group of epiphyseal necrose...
متن کاملPituitary gigantism.
A case of pituitary gigantism resulting from a pituitary adenoma which secreted growth hormone is described. The patient was successfully treated by surgery, which led to the normalisation of endogenous growth hormone secretion. An acceptable final height was achieved with high dose intramuscular testosterone treatment.
متن کاملGigantism caused by growth hormone secreting pituitary adenoma
Gigantism indicates excessive secretion of growth hormones (GH) during childhood when open epiphyseal growth plates allow for excessive linear growth. Case one involved a 14.7-year-old boy presented with extreme tall stature. His random serum GH level was 38.4 ng/mL, and failure of GH suppression was noted during an oral glucose tolerance test (OGTT; nadir serum GH, 22.7 ng/mL). Magnetic resona...
متن کاملPegvisomant therapy in pituitary gigantism: successful treatment in a 12-year-old girl.
OBJECTIVE The use of a growth hormone (GH) receptor antagonist, pegvisomant has shown great promise in adults with acromegaly, but experience in paediatric patients is lacking. We aimed to describe the results of pegvisomant therapy in a 12-year-old girl with an aggressive GH-secreting pituitary tumour. DESIGN To evaluate the ability of pegvisomant therapy to control the effects of peripheral...
متن کاملClinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.
Despite being a classical growth disorder, pituitary gigantism has not been studied previously in a standardized way. We performed a retrospective, multicenter, international study to characterize a large series of pituitary gigantism patients. We included 208 patients (163 males; 78.4%) with growth hormone excess and a current/previous abnormal growth velocity for age or final height >2 s.d. a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1939
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.14.79.203